Adipocyte PHLPP2 inhibition prevents obesity-induced fatty liver

Increased adiposity confers risk for systemic insulin resistance and type 2 diabetes (T2D), but mechanisms underlying this pathogenic inter-organ crosstalk are incompletely understood. We find PHLPP2 (PH domain and leucine rich repeat protein phosphatase 2), recently identified as the Akt Ser473 pho...

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Detalles Bibliográficos
Autores principales: Kim, KyeongJin, Kang, Jin Ku, Jung, Young Hoon, Lee, Sang Bae, Rametta, Raffaela, Dongiovanni, Paola, Valenti, Luca, Pajvani, Utpal B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988046/
https://www.ncbi.nlm.nih.gov/pubmed/33758172
http://dx.doi.org/10.1038/s41467-021-22106-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988046/
https://www.ncbi.nlm.nih.gov/pubmed/33758172
http://dx.doi.org/10.1038/s41467-021-22106-2

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