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Distinct DNA methylation patterns associated with treatment resistance in metastatic castration resistant prostate cancer
Androgens are a major driver of prostate cancer (PCa) and continue to be a critical treatment target for advanced disease, which includes castration therapy and antiandrogens. However, resistance to these therapies leading to metastatic castration-resistant prostate cancer (mCRPC), and the emergence...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988053/ https://www.ncbi.nlm.nih.gov/pubmed/33758253 http://dx.doi.org/10.1038/s41598-021-85812-3 |