The M-phase regulatory phosphatase PP2A-B55δ opposes protein kinase A on Arpp19 to initiate meiotic division

Oocytes are held in meiotic prophase for prolonged periods until hormonal signals trigger meiotic divisions. Key players of M-phase entry are the opposing Cdk1 kinase and PP2A-B55δ phosphatase. In Xenopus, the protein Arpp19, phosphorylated at serine 67 by Greatwall, plays an essential role in inhib...

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Detalles Bibliográficos
Autores principales: Lemonnier, Tom, Daldello, Enrico Maria, Poulhe, Robert, Le, Tran, Miot, Marika, Lignières, Laurent, Jessus, Catherine, Dupré, Aude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988065/
https://www.ncbi.nlm.nih.gov/pubmed/33758202
http://dx.doi.org/10.1038/s41467-021-22124-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988065/
https://www.ncbi.nlm.nih.gov/pubmed/33758202
http://dx.doi.org/10.1038/s41467-021-22124-0

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