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Gestational intermittent hyperoxia rescues murine genetic congenital heart disease in part

Cardiac development is a dynamic process, temporally and spatially. When disturbed, it leads to congenital cardiac anomalies that affect approximately 1% of live births. Genetic variants in several loci lead to anomalies, with the transcription factor NKX2-5 being one of the largest. However, there...

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Detalles Bibliográficos
Autores principales: Doll, Cassandra F., Pereira, Natalia J., Hashimi, Mustafa S., Grindrod, Tabor J., Alkassis, Fariz F., Cai, Lawrence X., Milovanovic, Una, Sandino, Adriana I., Kasahara, Hideko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988122/
https://www.ncbi.nlm.nih.gov/pubmed/33758249
http://dx.doi.org/10.1038/s41598-021-85569-9