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Gestational intermittent hyperoxia rescues murine genetic congenital heart disease in part
Cardiac development is a dynamic process, temporally and spatially. When disturbed, it leads to congenital cardiac anomalies that affect approximately 1% of live births. Genetic variants in several loci lead to anomalies, with the transcription factor NKX2-5 being one of the largest. However, there...
Autores principales: | Doll, Cassandra F., Pereira, Natalia J., Hashimi, Mustafa S., Grindrod, Tabor J., Alkassis, Fariz F., Cai, Lawrence X., Milovanovic, Una, Sandino, Adriana I., Kasahara, Hideko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988122/ https://www.ncbi.nlm.nih.gov/pubmed/33758249 http://dx.doi.org/10.1038/s41598-021-85569-9 |
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