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The nickel-chelator dimethylglyoxime inhibits human amyloid beta peptide in vitro aggregation
One of the hallmarks of the most common neurodegenerative disease, Alzheimer’s disease (AD), is the extracellular deposition and aggregation of Amyloid Beta (Aβ)-peptides in the brain. Previous studies have shown that select metal ions, most specifically copper (Cu) and zinc (Zn) ions, have a synerg...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988135/ https://www.ncbi.nlm.nih.gov/pubmed/33758258 http://dx.doi.org/10.1038/s41598-021-86060-1 |