Investigating the Role of Indoleamine 2,3-Dioxygenase in Acute Myeloid Leukemia: A Systematic Review

Background: The immunomodulatory enzyme, indoleamine 2,3-dioxygenase (IDO) facilitates tryptophan catabolism at the rate-limiting step of the kynurenine (Kyn) pathway. IDO expression and elevations in Kyn metabolites are associated with immunosuppressive tumor microenvironment including T cell proli...

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Detalles Bibliográficos
Autores principales: Wells, Georgia, Kennedy, Paul T., Dahal, Lekh N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988196/
https://www.ncbi.nlm.nih.gov/pubmed/33777052
http://dx.doi.org/10.3389/fimmu.2021.651687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988196/
https://www.ncbi.nlm.nih.gov/pubmed/33777052
http://dx.doi.org/10.3389/fimmu.2021.651687

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