Cargando…

Investigating the Role of Indoleamine 2,3-Dioxygenase in Acute Myeloid Leukemia: A Systematic Review

Background: The immunomodulatory enzyme, indoleamine 2,3-dioxygenase (IDO) facilitates tryptophan catabolism at the rate-limiting step of the kynurenine (Kyn) pathway. IDO expression and elevations in Kyn metabolites are associated with immunosuppressive tumor microenvironment including T cell proli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wells, Georgia, Kennedy, Paul T., Dahal, Lekh N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988196/ https://www.ncbi.nlm.nih.gov/pubmed/33777052 http://dx.doi.org/10.3389/fimmu.2021.651687

Ejemplares similares

Editorial: Targeting Indoleamine 2,3-dioxygenases and Tryptophan Dioxygenase for Cancer Immunotherapy
por: Brochez, Lieve, et al.
Publicado: (2021)

The Role of Indoleamine-2,3-Dioxygenase in Cancer Development, Diagnostics, and Therapy
por: Hornyák, Lilla, et al.
Publicado: (2018)

Indoleamine 2,3-Dioxygenase and Tolerance: Where Are We Now?
por: Mellor, Andrew L., et al.
Publicado: (2017)

The role of indoleamine 2,3-dioxygenase 1 in early-onset post-stroke depression
por: Chen, Hengshu, et al.
Publicado: (2023)

Targeting Indoleamine 2,3-Dioxygenase 1: Fighting Cancers via Dormancy Regulation
por: Yang, Chao, et al.
Publicado: (2021)

Indoleamine 2,3-Dioxygenase 1: A Promising Therapeutic Target in Malignant Tumor
por: Song, Xiaotian, et al.
Publicado: (2021)

Investigation of the Tissue Distribution and Physiological Roles of Indoleamine 2,3-Dioxygenase-2
por: Jusof, Felicita F, et al.
Publicado: (2017)

Overexpression of indoleamine 2,3-dioxygenase correlates with regulatory T cell phenotype in acute myeloid leukemia patients with normal karyotype
por: Arandi, Nargess, et al.
Publicado: (2018)

A Multifaceted Role of Tryptophan Metabolism and Indoleamine 2,3-Dioxygenase Activity in Aspergillus fumigatus–Host Interactions
por: Choera, Tsokyi, et al.
Publicado: (2018)

Localization of Indoleamine 2,3-Dioxygenase-1 and Indoleamine 2,3-Dioxygenase-2 at the Human Maternal-Fetal Interface
por: Kudo, Yoshiki, et al.
Publicado: (2020)

Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia
por: Folgiero, Valentina, et al.
Publicado: (2013)

High Indoleamine 2,3-Dioxygenase Is Correlated With Microvessel Density and Worse Prognosis in Breast Cancer
por: Wei, Lijuan, et al.
Publicado: (2018)

What May Constrain the Success of Indoleamine 2,3-Dioxygenase 1 Inhibitors in Cancer Immunotherapy?
por: Eleftheriadis, Theodoros
Publicado: (2018)

The role of placental indoleamine 2,3-dioxygenase in human pregnancy
por: Kudo, Yoshiki
Publicado: (2013)

Role of indoleamine 2,3-dioxygenase in pathology of the gastrointestinal tract
por: Acovic, Aleksandar, et al.
Publicado: (2018)

Role of indoleamine 2,3-dioxygenase in testicular immune-privilege
por: Gualdoni, Gisela S., et al.
Publicado: (2019)

Associations of microbial and indoleamine-2,3-dioxygenase-derived tryptophan metabolites with immune activation in healthy adults
por: Riazati, Niknaz, et al.
Publicado: (2022)

Interleukin-6 and indoleamine-2,3-dioxygenase as potential adjuvant targets for Papillomavirus-related tumors immunotherapy
por: Pagni, Roberta Liberato, et al.
Publicado: (2022)

Indoleamine 2,3-dioxygenase 1 signaling orchestrates immune tolerance in Echinococcus multilocularis-infected mice
por: Meng, Ru, et al.
Publicado: (2022)

A narrative review of the roles of indoleamine 2,3-dioxygenase and tryptophan-2,3-dioxygenase in liver diseases
por: Zhou, Qihui, et al.
Publicado: (2021)

A novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression
por: Mangaonkar, Abhishek, et al.
Publicado: (2017)

Disease Tolerance Mediated by Phosphorylated Indoleamine-2,3 Dioxygenase Confers Resistance to a Primary Fungal Pathogen
por: de Araújo, Eliseu Frank, et al.
Publicado: (2017)

Activation of the Regulatory T-Cell/Indoleamine 2,3-Dioxygenase Axis Reduces Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice
por: Forteza, Maria J., et al.
Publicado: (2018)

Indoleamine 2,3-Dioxygenase Cannot Inhibit Chlamydia trachomatis Growth in HL-60 Human Neutrophil Granulocytes
por: Virok, Dezső P., et al.
Publicado: (2021)

GBP1 Facilitates Indoleamine 2,3-Dioxygenase Extracellular Secretion to Promote the Malignant Progression of Lung Cancer
por: Meng, Yinnan, et al.
Publicado: (2021)

Targeting the indoleamine 2,3-dioxygenase pathway in cancer
por: Moon, Yong Wha, et al.
Publicado: (2015)

The Role of Indoleamine 2,3-Dioxygenase in Diethylnitrosamine-Induced Liver Carcinogenesis
por: Shibata, Yuhei, et al.
Publicado: (2016)

Indoleamine 2,3-Dioxygenase Expression Pattern in the Tumor Microenvironment Predicts Clinical Outcome in Early Stage Cervical Cancer
por: Heeren, A. Marijne, et al.
Publicado: (2018)

Expression of Indoleamine 2,3-Dioxygenase Induced by IFN-γ and TNF-α as Potential Biomarker of Prostate Cancer Progression
por: Banzola, Irina, et al.
Publicado: (2018)

The Proteasome Inhibitor Bortezomib Controls Indoleamine 2,3-Dioxygenase 1 Breakdown and Restores Immune Regulation in Autoimmune Diabetes
por: Mondanelli, Giada, et al.
Publicado: (2017)

Targeting Indoleamine 2,3-Dioxygenase in Cancer Models Using the Novel Small Molecule Inhibitor NTRC 3883-0
por: Grobben, Yvonne, et al.
Publicado: (2021)

The Mechanism of Substrate Inhibition in Human Indoleamine 2,3-Dioxygenase
por: Efimov, Igor, et al.
Publicado: (2012)

Indoleamine-2,3-dioxygenase activity induces neutrophil apoptosis
por: Van der Sluijs, K, et al.
Publicado: (2011)

Indoleamine-2,3-dioxygenase activity in experimental human endotoxemia
por: Padberg, Jan-Sören, et al.
Publicado: (2012)

Advances in indoleamine 2,3-dioxygenase 1 medicinal chemistry
por: Coletti, Alice, et al.
Publicado: (2017)

Emerging Roles on Immunological Effect of Indoleamine 2,3-Dioxygenase in Liver Injuries
por: Xu, Lingyan, et al.
Publicado: (2021)

Indoleamine-2,3-Dioxygenase as a Perioperative Marker of the Immune System
por: Bello, Corina, et al.
Publicado: (2021)

Commentary: Indoleamine 2,3-Dioxygenase-Expressing Aortic Plasmacytoid Dendritic Cells Protect against Atherosclerosis by Induction of Regulatory T Cells
por: Maffia, Pasquale, et al.
Publicado: (2017)

Indoleamine 2,3-Dioxygenase 1 Inhibitor-Loaded Nanosheets Enhance CAR-T Cell Function in Esophageal Squamous Cell Carcinoma
por: Shao, Jingwen, et al.
Publicado: (2021)

Association of Microbial Tryptophan Metabolites and Indoleamine-2,3-Dioxygenase with Immune Activity in Healthy Adults
por: Riazati, Niknaz, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hi0qveumcdlagfq88kom7d5ohr