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Neutrophil-Associated Inflammatory Changes in the Pre-Diabetic Pancreas of Early-Age NOD Mice

A growing body of evidence indicates that neutrophils are the first major leukocyte population accumulating inside the pancreas even before the onset of a lymphocytic-driven impairment of functional beta cells in type 1 diabetes mellitus (T1D). In humans, pancreata from T1D deceased donors exhibit s...

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Detalles Bibliográficos
Autores principales: Garciafigueroa, Yesica, Phillips, Brett E., Engman, Carl, Trucco, Massimo, Giannoukakis, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988208/
https://www.ncbi.nlm.nih.gov/pubmed/33776903
http://dx.doi.org/10.3389/fendo.2021.565981