Cargando…

Neutrophil-Associated Inflammatory Changes in the Pre-Diabetic Pancreas of Early-Age NOD Mice

A growing body of evidence indicates that neutrophils are the first major leukocyte population accumulating inside the pancreas even before the onset of a lymphocytic-driven impairment of functional beta cells in type 1 diabetes mellitus (T1D). In humans, pancreata from T1D deceased donors exhibit s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Garciafigueroa, Yesica, Phillips, Brett E., Engman, Carl, Trucco, Massimo, Giannoukakis, Nick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988208/ https://www.ncbi.nlm.nih.gov/pubmed/33776903 http://dx.doi.org/10.3389/fendo.2021.565981

Ejemplares similares

Co-Stimulation-Impaired Bone Marrow-Derived Dendritic Cells Prevent Dextran Sodium Sulfate-Induced Colitis in Mice
por: Engman, Carl, et al.
Publicado: (2018)

Tolerogenic Dendritic Cells and T-Regulatory Cells at the Clinical Trials Crossroad for the Treatment of Autoimmune Disease; Emphasis on Type 1 Diabetes Therapy
por: Phillips, Brett Eugene, et al.
Publicado: (2019)

Clinical Tolerogenic Dendritic Cells: Exploring Therapeutic Impact on Human Autoimmune Disease
por: Phillips, Brett Eugene, et al.
Publicado: (2017)

Involvement of Suppressive B-Lymphocytes in the Mechanism of Tolerogenic Dendritic Cell Reversal of Type 1 Diabetes in NOD Mice
por: Di Caro, Valentina, et al.
Publicado: (2014)

Improvement in insulin sensitivity and prevention of high fat diet-induced liver pathology using a CXCR2 antagonist
por: Phillips, Brett E., et al.
Publicado: (2022)

Arrest in the Progression of Type 1 Diabetes at the Mid-Stage of Insulitic Autoimmunity Using an Autoantigen-Decorated All-trans Retinoic Acid and Transforming Growth Factor Beta-1 Single Microparticle Formulation
por: Phillips, Brett E., et al.
Publicado: (2021)

Current State of Type 1 Diabetes Immunotherapy: Incremental Advances, Huge Leaps, or More of the Same?
por: Phillips, Brett, et al.
Publicado: (2011)

Human Hemangioblast-Derived Mesenchymal Stem Cells Promote Islet Engraftment in a Minimal Islet Mass Transplantation Model in Mice
por: Bertera, Suzanne, et al.
Publicado: (2021)

Uncoupling hepatic insulin resistance – hepatic inflammation to improve insulin sensitivity and to prevent impaired metabolism-associated fatty liver disease in type 2 diabetes
por: Niranjan, Sitara, et al.
Publicado: (2023)

Aberrant expression of transglutaminase 2 in pancreas and thymus of NOD mice underscores the importance of deamidation in neoantigen generation
por: Callebaut, Aїsha, et al.
Publicado: (2022)

Phase I (Safety) Study of Autologous Tolerogenic Dendritic Cells in Type 1 Diabetic Patients
por: Giannoukakis, Nick, et al.
Publicado: (2011)

Inflammatory status of the pancreas in NOD mice that do not develop overt diabetes
por: Catrina, Ana-Maria, et al.
Publicado: (2021)

Editorial: Diabetes and non-alcoholic fatty liver disease: points of physiological and mechanistic intersection and current co-therapeutic approaches
por: Giannoukakis, Nick, et al.
Publicado: (2023)

Preventing type 1 diabetes in late-stage pre-diabetic NOD mice with insulin: A central role for alum as adjuvant
por: Martens, Pieter-Jan, et al.
Publicado: (2022)

Sustained high glucose intake accelerates type 1 diabetes in NOD mice
por: Li, Xiangqian, et al.
Publicado: (2022)

The Role of NOD Mice in Type 1 Diabetes Research: Lessons from the Past and Recommendations for the Future
por: Chen, Yi-Guang, et al.
Publicado: (2018)

Case Report: Anastrozole as a monotherapy for pre-pubertal children with non-classic congenital adrenal hyperplasia
por: Liu, Sandy C., et al.
Publicado: (2023)

Gene Expression Analysis of the Pre-Diabetic Pancreas to Identify Pathogenic Mechanisms and Biomarkers of Type 1 Diabetes
por: Yip, Linda, et al.
Publicado: (2020)

Evolution of Hepatic Steatosis to Fibrosis and Adenoma Formation in Liver-Specific Growth Hormone Receptor Knockout Mice
por: Fan, Yong, et al.
Publicado: (2014)

Leveraging the strengths of mice, human stem cells, and organoids to model pancreas development and diabetes
por: Lorberbaum, David S., et al.
Publicado: (2022)

It’s Time to Bring Dendritic Cell Therapy to Type 1 Diabetes
por: Creusot, Rémi J., et al.
Publicado: (2014)

Large Gliadin Peptides Detected in the Pancreas of NOD and Healthy Mice following Oral Administration
por: Bruun, Susanne W., et al.
Publicado: (2016)

Altered Metabolic Signature in Pre-Diabetic NOD Mice
por: Madsen, Rasmus, et al.
Publicado: (2012)

Editorial: Pancreas Imaging Across the Spectrum
por: Linnemann, Amelia K., et al.
Publicado: (2021)

Autoimmune Inflammation and Insulin Resistance: Hallmarks So Far and Yet So Close to Explain Diabetes Endotypes
por: Petrelli, Alessandra, et al.
Publicado: (2021)

Pancreas Whole Tissue Transcriptomics Highlights the Role of the Exocrine Pancreas in Patients With Recently Diagnosed Type 1 Diabetes
por: Välikangas, Tommi, et al.
Publicado: (2022)

Corrigendum to “Large Gliadin Peptides Detected in the Pancreas of NOD and Healthy Mice following Oral Administration”
por: Bruun, Susanne W., et al.
Publicado: (2017)

The Kinetics of Plasmacytoid Dendritic Cell Accumulation in the Pancreas of the NOD Mouse during the Early Phases of Insulitis
por: Welzen-Coppens, Jojanneke M. C., et al.
Publicado: (2013)

Phagocytosis and Efferocytosis by Resident Macrophages in the Mouse Pancreas
por: Parv, Kristel, et al.
Publicado: (2021)

Circadian rhythms and pancreas physiology: A review
por: Chan, Karl, et al.
Publicado: (2022)

Editorial: Interaction between endocrine and exocrine pancreas
por: Li, Ling, et al.
Publicado: (2022)

Human stem cell derived beta-like cells engineered to present PD-L1 improve transplant survival in NOD mice carrying human HLA class I
por: Santini-González, Jorge, et al.
Publicado: (2022)

Quantitative Magnetic Resonance Imaging of the Pancreas of Individuals With Diabetes
por: Virostko, John
Publicado: (2020)

Identification of a Cardiac Specific Protein Transduction Domain by In Vivo Biopanning Using a M13 Phage Peptide Display Library in Mice
por: Zahid, Maliha, et al.
Publicado: (2010)

Role of SST, CORT and ghrelin and its receptors at the endocrine pancreas
por: Beléen, Chanclón, et al.
Publicado: (2012)

Ontogeny of Neuro-Insular Complexes and Islets Innervation in the Human Pancreas
por: Proshchina, Alexandra E., et al.
Publicado: (2014)

Mesoscopic Optical Imaging of the Pancreas—Revisiting Pancreatic Anatomy and Pathophysiology
por: Alanentalo, Tomas, et al.
Publicado: (2021)

Editorial: Footprints of Immune Cells in the Type 1 Diabetic Pancreas
por: Brusko, Todd M., et al.
Publicado: (2021)

Pancreas Optical Clearing and 3-D Microscopy in Health and Diabetes
por: Campbell-Thompson, Martha, et al.
Publicado: (2021)

NOD mouse dorsal root ganglia display morphological and gene expression defects before and during autoimmune diabetes development
por: Corral-Pujol, Marta, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_h5ntif6d6i8l453f3qn2l0c35f