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Silencing XIST mitigated lipopolysaccharide (LPS)-induced inflammatory injury in human lung fibroblast WI-38 cells through modulating miR-30b-5p/CCL16 axis and TLR4/NF-κB signaling pathway

BACKGROUND: Emerging evidence shows that long noncoding RNA (lncRNA) has been a novel insight in various diseases, including pneumonia. Even though lncRNA X-inactive-specific transcript (XIST) is well studied, its role in pneumonia remains to be largely unrevealed. METHODS: Expression of XIST, miRNA...

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Detalles Bibliográficos
Autores principales: Xu, Jiahui, Li, Honggui, Lv, Ying, Zhang, Chang, Chen, Yiting, Yu, Dezhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988359/
https://www.ncbi.nlm.nih.gov/pubmed/33817304
http://dx.doi.org/10.1515/biol-2021-0005