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Generation of six induced pluripotent stem cell lines from patients with amyotrophic lateral sclerosis with associated genetic mutations in either FUS or ANXA11

Amyotrophic lateral sclerosis (ALS) is characterized by degeneration of upper and lower motor neurons, causing gradual paralysis, and resulting in death 3–5 years from diagnosis. ALS causative mutations have been identified in multiple genes, including Fused in sarcoma (FUS), and recently characteri...

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Detalles Bibliográficos
Autores principales: Hedges, Erin C., Topp, Simon, Shaw, Christopher E., Nishimura, Agnes L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988463/
https://www.ncbi.nlm.nih.gov/pubmed/33610019
http://dx.doi.org/10.1016/j.scr.2021.102246