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Type I and type V procollagen triple helix uses different subsets of the molecular ensemble for lysine posttranslational modifications in the rER

Collagen is the most abundant protein in humans. It has a characteristic triple-helix structure and is heavily posttranslationally modified. The complex biosynthesis of collagen involves processing by many enzymes and chaperones in the rough endoplasmic reticulum. Lysyl hydroxylase 1 (LH1) is requir...

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Detalles Bibliográficos
Autores principales: Ishikawa, Yoshihiro, Taga, Yuki, Zientek, Keith, Mizuno, Nobuyo, Salo, Antti M., Semenova, Olesya, Tufa, Sara F., Keene, Douglas R., Holden, Paul, Mizuno, Kazunori, Gould, Douglas B., Myllyharju, Johanna, Bächinger, Hans Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988497/
https://www.ncbi.nlm.nih.gov/pubmed/33631195
http://dx.doi.org/10.1016/j.jbc.2021.100453