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Type I and type V procollagen triple helix uses different subsets of the molecular ensemble for lysine posttranslational modifications in the rER
Collagen is the most abundant protein in humans. It has a characteristic triple-helix structure and is heavily posttranslationally modified. The complex biosynthesis of collagen involves processing by many enzymes and chaperones in the rough endoplasmic reticulum. Lysyl hydroxylase 1 (LH1) is requir...
Autores principales: | Ishikawa, Yoshihiro, Taga, Yuki, Zientek, Keith, Mizuno, Nobuyo, Salo, Antti M., Semenova, Olesya, Tufa, Sara F., Keene, Douglas R., Holden, Paul, Mizuno, Kazunori, Gould, Douglas B., Myllyharju, Johanna, Bächinger, Hans Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988497/ https://www.ncbi.nlm.nih.gov/pubmed/33631195 http://dx.doi.org/10.1016/j.jbc.2021.100453 |
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