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Tubulin acetylation increases cytoskeletal stiffness to regulate mechanotransduction in striated muscle

Microtubules tune cytoskeletal stiffness, which affects cytoskeletal mechanics and mechanotransduction of striated muscle. While recent evidence suggests that microtubules enriched in detyrosinated α-tubulin regulate these processes in healthy muscle and increase them in disease, the possible contri...

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Detalles Bibliográficos
Autores principales: Coleman, Andrew K., Joca, Humberto C., Shi, Guoli, Lederer, W. Jonathan, Ward, Christopher W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988512/
https://www.ncbi.nlm.nih.gov/pubmed/33740038
http://dx.doi.org/10.1085/jgp.202012743