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Tubulin acetylation increases cytoskeletal stiffness to regulate mechanotransduction in striated muscle
Microtubules tune cytoskeletal stiffness, which affects cytoskeletal mechanics and mechanotransduction of striated muscle. While recent evidence suggests that microtubules enriched in detyrosinated α-tubulin regulate these processes in healthy muscle and increase them in disease, the possible contri...
Autores principales: | Coleman, Andrew K., Joca, Humberto C., Shi, Guoli, Lederer, W. Jonathan, Ward, Christopher W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988512/ https://www.ncbi.nlm.nih.gov/pubmed/33740038 http://dx.doi.org/10.1085/jgp.202012743 |
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