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Novel insights into sarcomere regulatory systems control of cardiac thin filament activation
Our review focuses on sarcomere regulatory mechanisms with a discussion of cardiac-specific modifications to the three-state model of thin filament activation from a blocked to closed to open state. We discuss modulation of these thin filament transitions by Ca(2+), by crossbridge interactions, and...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988513/ https://www.ncbi.nlm.nih.gov/pubmed/33740037 http://dx.doi.org/10.1085/jgp.202012777 |