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Pharmacogenetics–Based Preliminary Algorithm to Predict the Incidence of Infection in Patients Receiving Cytotoxic Chemotherapy for Hematological Malignancies: A Discovery Cohort

Introduction: Infections in hematological cancer patients are common and usually life-threatening; avoiding them could decrease morbidity, mortality, and cost. Genes associated with antineoplastics’ pharmacokinetics or with the immune/inflammatory response could explain variability in infection occu...

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Detalles Bibliográficos
Autores principales: Martinez, Matias F., Alveal, Enzo, Soto, Tomas G., Bustamante, Eva I., Ávila, Fernanda, Bangdiwala, Shrikant I., Flores, Ivonne, Monterrosa, Claudia, Morales, Ricardo, Varela, Nelson M., Fohner, Alison E., Quiñones, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988592/
https://www.ncbi.nlm.nih.gov/pubmed/33776761
http://dx.doi.org/10.3389/fphar.2021.602676