FLI1 and ERG protein degradation is regulated via Cathepsin B lysosomal pathway in human dermal microvascular endothelial cells

OBJECTIVES: Friend leukemia integration 1 and erythroblast transformation‐specific, important regulators of endothelial cell homeostasis, are reduced in microvascular endothelial cells in scleroderma patients, and their deficiency has been implicated in disease pathogenesis. The goal of this study w...

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Detalles Bibliográficos
Autores principales: Mazzotta, Celestina, Marden, Grace, Farina, Alessandra, Bujor, Andreea, Trojanowski, Marcin A., Trojanowska, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988617/
https://www.ncbi.nlm.nih.gov/pubmed/32979864
http://dx.doi.org/10.1111/micc.12660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988617/
https://www.ncbi.nlm.nih.gov/pubmed/32979864
http://dx.doi.org/10.1111/micc.12660

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