Multi-cohort analysis of host immune response identifies conserved protective and detrimental modules associated with severity across viruses

Viral infections induce a conserved host response distinct from bacterial infections. We hypothesized that the conserved response is associated with disease severity and is distinct between patients with different outcomes. To test this, we integrated 4,780 blood transcriptome profiles from patients...

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Detalles Bibliográficos
Autores principales: Zheng, Hong, Rao, Aditya M., Dermadi, Denis, Toh, Jiaying, Murphy Jones, Lara, Donato, Michele, Liu, Yiran, Su, Yapeng, Dai, Cheng L., Kornilov, Sergey A., Karagiannis, Minas, Marantos, Theodoros, Hasin-Brumshtein, Yehudit, He, Yudong D., Giamarellos-Bourboulis, Evangelos J., Heath, James R., Khatri, Purvesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988739/
https://www.ncbi.nlm.nih.gov/pubmed/33765435
http://dx.doi.org/10.1016/j.immuni.2021.03.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988739/
https://www.ncbi.nlm.nih.gov/pubmed/33765435
http://dx.doi.org/10.1016/j.immuni.2021.03.002

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