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Multiscale molecular profiling of pathological bone resolves sexually dimorphic control of extracellular matrix composition

Collagen assembly during development is essential for successful matrix mineralisation, which determines bone quality and mechanocompetence. However, the biochemical and structural perturbations that drive pathological skeletal collagen configuration remain unclear. Deletion of vascular endothelial...

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Detalles Bibliográficos
Autores principales: Sharma, Aikta, Goring, Alice, Johnson, Peter B., Emery, Roger J. H., Hesse, Eric, Boyde, Alan, Olsen, Bjorn R., Pitsillides, Andrew A., Oreffo, Richard O. C., Mahajan, Sumeet, Clarkin, Claire E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988766/
https://www.ncbi.nlm.nih.gov/pubmed/33563616
http://dx.doi.org/10.1242/dmm.048116