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Multiscale molecular profiling of pathological bone resolves sexually dimorphic control of extracellular matrix composition
Collagen assembly during development is essential for successful matrix mineralisation, which determines bone quality and mechanocompetence. However, the biochemical and structural perturbations that drive pathological skeletal collagen configuration remain unclear. Deletion of vascular endothelial...
Autores principales: | Sharma, Aikta, Goring, Alice, Johnson, Peter B., Emery, Roger J. H., Hesse, Eric, Boyde, Alan, Olsen, Bjorn R., Pitsillides, Andrew A., Oreffo, Richard O. C., Mahajan, Sumeet, Clarkin, Claire E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988766/ https://www.ncbi.nlm.nih.gov/pubmed/33563616 http://dx.doi.org/10.1242/dmm.048116 |
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