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Hepatitis B virus induces sorafenib resistance in liver cancer via upregulation of cIAP2 expression

BACKGROUND: HBV promotes cell survival by upregulating the expression of the cellular inhibitor of apoptosis protein 2 (cIAP2), however whether it is involved in HBV-induced sorafenib resistance in liver cancer remains unclear. METHODS: cIAP2 overexpression and knockdown was adopted to assess the in...

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Detalles Bibliográficos
Autores principales: Zhang, Shouhua, Li, Nuoya, Sheng, Yanling, Chen, Wen, Ma, Qiangliang, Yu, Xin, Lian, Jianping, Zeng, Junquan, Yang, Yipeng, Yan, Jinlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988944/
https://www.ncbi.nlm.nih.gov/pubmed/33757557
http://dx.doi.org/10.1186/s13027-021-00359-2