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Artesunate ameliorates cigarette smoke-induced airway remodelling via PPAR-γ/TGF-β1/Smad2/3 signalling pathway

BACKGROUND: Airway remodelling is the major pathological feature of chronic obstructive pulmonary disease (COPD), and leads to poorly reversible airway obstruction. Current pharmacological interventions are ineffective in controlling airway remodelling. In the present study, we investigated the pote...

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Detalles Bibliográficos
Autores principales: Pan, Kunming, Lu, Juanjuan, Song, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989207/
https://www.ncbi.nlm.nih.gov/pubmed/33757521
http://dx.doi.org/10.1186/s12931-021-01687-y