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Identifying Primate ACE2 Variants That Confer Resistance to SARS-CoV-2

SARS-CoV-2 infects humans through the binding of viral S-protein (spike protein) to human angiotensin I converting enzyme 2 (ACE2). The structure of the ACE2-S-protein complex has been deciphered and we focused on the 27 ACE2 residues that bind to S-protein. From human sequence databases, we identif...

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Detalles Bibliográficos
Autores principales: Bhattacharjee, Maloyjo Joyraj, Lin, Jinn-Jy, Chang, Chih-Yao, Chiou, Yu-Ting, Li, Tian-Neng, Tai, Chia-Wei, Shiu, Tz-Fan, Chen, Chi-An, Chou, Chia-Yi, Chakraborty, Paromita, Tseng, Yan Yuan, Wang, Lily Hui-Ching, Li, Wen-Hsiung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989403/
https://www.ncbi.nlm.nih.gov/pubmed/33674876
http://dx.doi.org/10.1093/molbev/msab060