AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation

BACKGROUND: S‐adenosylmethionine decarboxylase proenzyme (AMD1) is a key enzyme involved in the synthesis of spermine (SPM) and spermidine (SPD), which are associated with multifarious cellular processes. It is also found to be an oncogene in multiple cancers and a potential target for tumor therapy...

Descripción completa

Detalles Bibliográficos
Autores principales: Bian, Xinyu, Shi, Dongmin, Xing, Kailin, Zhou, Hongxin, Lu, Lili, Yu, Dahai, Wu, Weizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989706/
https://www.ncbi.nlm.nih.gov/pubmed/33783988
http://dx.doi.org/10.1002/ctm2.352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989706/
https://www.ncbi.nlm.nih.gov/pubmed/33783988
http://dx.doi.org/10.1002/ctm2.352

Ejemplares similares