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Brodifacoum pharmacokinetics in acute human poisoning: implications for estimating duration of vitamin K therapy

Standard of care follow-up therapy for patients poisoned by long-acting anticoagulant rodenticides (LAARs) is daily high-dose (up to 100 mg per day) oral vitamin K1 (VK(1)) for weeks to months to over a year. The availability of CLIA-certified quantitative testing for plasma LAAR concentrations can...

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Detalles Bibliográficos
Autores principales: Nosal, Daniel G., van Breemen, Richard B., Haffner, John W., Rubinstein, Israel, Feinstein, Douglas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990043/
https://www.ncbi.nlm.nih.gov/pubmed/33768191
http://dx.doi.org/10.1080/24734306.2021.1887637