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Enhancing antibody-dependent cell-mediated cytotoxicity: a strategy for improving antibody-based immunotherapy

The targeting of surface antigens expressed on tumor cells by monoclonal antibodies (mAbs) has revolutionized cancer therapeutics. One mechanism of action of antibody-based immunotherapy is the activation of immune effector cells to mediate antibody-dependent cell-mediated cytotoxicity (ADCC). This...

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Detalles Bibliográficos
Autores principales: Zahavi, David, AlDeghaither, Dalal, O’Connell, Allison, Weiner, Louis M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990127/
https://www.ncbi.nlm.nih.gov/pubmed/33928217
http://dx.doi.org/10.1093/abt/tby002