Resveratrol Reduces COMPopathy in Mice Through Activation of Autophagy

Misfolding mutations in cartilage oligomeric matrix protein (COMP) cause it to be retained within the endoplasmic reticulum (ER) of chondrocytes, stimulating a multitude of damaging cellular responses including ER stress, inflammation, and oxidative stress, which ultimately culminates in the death o...

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Detalles Bibliográficos
Autores principales: Hecht, Jacqueline T, Coustry, Francoise, Veerisetty, Alka C, Hossain, Mohammad G, Posey, Karen L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990140/
https://www.ncbi.nlm.nih.gov/pubmed/33778324
http://dx.doi.org/10.1002/jbm4.10456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990140/
https://www.ncbi.nlm.nih.gov/pubmed/33778324
http://dx.doi.org/10.1002/jbm4.10456

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