Low‐Dose Tamoxifen Induces Significant Bone Formation in Mice

Use of the selective estrogen receptor modulator Tamoxifen (TAM) is a mainstay to induce conditional expression of Cre recombinase in transgenic laboratory mice. To excise β‐catenin(fl/fl) in 28‐day‐old male and female Prrx1‐CreER/β‐catenin(fl/fl) mice (C57BL/6), we utilized TAM at 150 mg/kg; despit...

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Detalles Bibliográficos
Autores principales: Xie, Zhihui, McGrath, Cody, Sankaran, Jeyantt, Styner, Maya, Little‐Letsinger, Sarah, Dudakovic, Amel, van Wijnen, Andre J, Rubin, Janet, Sen, Buer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990151/
https://www.ncbi.nlm.nih.gov/pubmed/33778320
http://dx.doi.org/10.1002/jbm4.10450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990151/
https://www.ncbi.nlm.nih.gov/pubmed/33778320
http://dx.doi.org/10.1002/jbm4.10450

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