MicroRNA-212-5p and its target PAFAH1B2 suppress vascular proliferation and contraction via the downregulation of RhoA

Vascular remodeling and contraction contribute to the development of hypertension. We investigated the role of miR-212-5p and its downstream target in vascular smooth muscle cell (VSMC) proliferation, migration, and contraction. MicroRNA microarray and PCR analyses showed that miR-212-5p expression...

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Detalles Bibliográficos
Autores principales: Kim, Gwi Ran, Zhao, Tingwei, Kee, Hae Jin, Kee, Seung-Jung, Jeong, Myung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990166/
https://www.ncbi.nlm.nih.gov/pubmed/33760887
http://dx.doi.org/10.1371/journal.pone.0249146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990166/
https://www.ncbi.nlm.nih.gov/pubmed/33760887
http://dx.doi.org/10.1371/journal.pone.0249146

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