Deficiency in CCR2 increases susceptibility of mice to infection with an intracellular pathogen, Francisella tularensis LVS, but does not impair development of protective immunity

CCR2 is the major chemokine receptor that regulates appropriate trafficking of inflammatory monocytes, but the role of this chemokine receptor and its ligands during primary and secondary infection with intracellular infections remains incompletely understood. Here we used murine infection with the...

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Detalles Bibliográficos
Autores principales: Kurtz, Sherry L., De Pascalis, Roberto, Meierovics, Anda I., Elkins, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990183/
https://www.ncbi.nlm.nih.gov/pubmed/33760886
http://dx.doi.org/10.1371/journal.pone.0249142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990183/
https://www.ncbi.nlm.nih.gov/pubmed/33760886
http://dx.doi.org/10.1371/journal.pone.0249142

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