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Sagacity in antibody humanization for therapeutics, diagnostics and research purposes: considerations of antibody elements and their roles

The humanization of antibodies for therapeutics is a critical process that can determine the success of antibody drug development. However, the science underpinning this process remains elusive with different laboratories having very different methods. Well-funded laboratories can afford automated h...

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Detalles Bibliográficos
Autores principales: Ling, Wei-Li, Lua, Wai-Heng, Gan, Samuel Ken-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990220/
https://www.ncbi.nlm.nih.gov/pubmed/33928226
http://dx.doi.org/10.1093/abt/tbaa005