Cargando…
A high-content screen identifies the vulnerability of MYC-overexpressing cells to dimethylfasudil
A synthetic lethal effect arises when a cancer-associated change introduces a unique vulnerability to cancer cells that makes them unusually susceptible to a drug’s inhibitory activity. The synthetic lethal approach is attractive because it enables targeting of cancers harboring specific genomic or...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990233/ https://www.ncbi.nlm.nih.gov/pubmed/33760847 http://dx.doi.org/10.1371/journal.pone.0248355 |