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Aggregation of Aβ(40/42) chains in the presence of cyclic neuropeptides investigated by molecular dynamics simulations
Alzheimer’s disease is associated with the formation of toxic aggregates of amyloid beta (Aβ) peptides. Despite tremendous efforts, our understanding of the molecular mechanisms of aggregation, as well as cofactors that might influence it, remains incomplete. The small cyclic neuropeptide somatostat...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990313/ https://www.ncbi.nlm.nih.gov/pubmed/33711010 http://dx.doi.org/10.1371/journal.pcbi.1008771 |