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Lymphangiogenesis-inducing vaccines elicit potent and long-lasting T cell immunity against melanomas

In melanoma, the induction of lymphatic growth (lymphangiogenesis) has long been correlated with metastasis and poor prognosis, but we recently showed it can synergistically enhance cancer immunotherapy and boost T cell immunity. Here, we develop a translational approach for exploiting this “lymphan...

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Detalles Bibliográficos
Autores principales: Sasso, Maria Stella, Mitrousis, Nikolaos, Wang, Yue, Briquez, Priscilla S., Hauert, Sylvie, Ishihara, Jun, Hubbell, Jeffrey A., Swartz, Melody A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990326/
https://www.ncbi.nlm.nih.gov/pubmed/33762337
http://dx.doi.org/10.1126/sciadv.abe4362