Arginine methyltransferase PRMT5 negatively regulates cGAS-mediated antiviral immune response

Cyclic GMP-AMP synthase (cGAS) functions as an essential DNA sensor, which senses the cytoplasmic double-stranded DNA and activates the antiviral response. However, the posttranslational modification of cGAS remains to be fully understood and whether it has arginine methylation modification remains...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Dapeng, Yang, Min, Wang, Qiushi, Sun, Caiyu, Shi, Hongbiao, Jing, Weiqiang, Bi, Yuxuan, Shen, Xuecheng, Ma, Xiaomin, Qin, Zhenzhi, Lin, Yueke, Zhu, Lihui, Zhao, Yunxue, Cheng, Yeping, Han, Lihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990331/
https://www.ncbi.nlm.nih.gov/pubmed/33762328
http://dx.doi.org/10.1126/sciadv.abc1834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990331/
https://www.ncbi.nlm.nih.gov/pubmed/33762328
http://dx.doi.org/10.1126/sciadv.abc1834

Ejemplares similares