LncRNA GIRGL drives CAPRIN1-mediated phase separation to suppress glutaminase-1 translation under glutamine deprivation

Glutamine constitutes an essential source of both carbon and nitrogen for numerous biosynthetic processes. The first and rate-limiting step of glutaminolysis involves the generation of glutamate from glutamine, catalyzed by glutaminase-1 (GLS1). Shortages of glutamine result in reductions in GLS1, b...

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Detalles Bibliográficos
Autores principales: Wang, Ruijie, Cao, Leixi, Thorne, Rick Francis, Zhang, Xu Dong, Li, Jinming, Shao, Fengmin, Zhang, Lirong, Wu, Mian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990344/
https://www.ncbi.nlm.nih.gov/pubmed/33762340
http://dx.doi.org/10.1126/sciadv.abe5708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990344/
https://www.ncbi.nlm.nih.gov/pubmed/33762340
http://dx.doi.org/10.1126/sciadv.abe5708

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