Nilotinib Improves Bioenergetic Profiling in Brain Astroglia in the 3xTg Mouse Model of Alzheimer’s Disease

Current treatments targeting amyloid beta in Alzheimer’s disease (AD) have minimal efficacy, which results in a huge unmet medical need worldwide. Accumulating data suggest that brain mitochondrial dysfunction play a critical role in AD pathogenesis. Targeting cellular mechanisms associated with mit...

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Detalles Bibliográficos
Autores principales: Adlimoghaddam, Aida, Odero, Gary G, Glazner, Gordon, Turner, R. Scott, Albensi, Benedict C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2021
Materias:
Orginal Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990369/
https://www.ncbi.nlm.nih.gov/pubmed/33815876
http://dx.doi.org/10.14336/AD.2020.0910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990369/
https://www.ncbi.nlm.nih.gov/pubmed/33815876
http://dx.doi.org/10.14336/AD.2020.0910

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