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Nilotinib Improves Bioenergetic Profiling in Brain Astroglia in the 3xTg Mouse Model of Alzheimer’s Disease

Current treatments targeting amyloid beta in Alzheimer’s disease (AD) have minimal efficacy, which results in a huge unmet medical need worldwide. Accumulating data suggest that brain mitochondrial dysfunction play a critical role in AD pathogenesis. Targeting cellular mechanisms associated with mit...

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Detalles Bibliográficos
Autores principales:	Adlimoghaddam, Aida, Odero, Gary G, Glazner, Gordon, Turner, R. Scott, Albensi, Benedict C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JKL International LLC 2021
Materias:	Orginal Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990369/ https://www.ncbi.nlm.nih.gov/pubmed/33815876 http://dx.doi.org/10.14336/AD.2020.0910

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