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Hemochromatosis Mutations, Brain Iron Imaging, and Dementia in the UK Biobank Cohort
BACKGROUND: Brain iron deposition occurs in dementia. In European ancestry populations, the HFE p.C282Y variant can cause iron overload and hemochromatosis, mostly in homozygous males. OBJECTIVE: To estimate p.C282Y associations with brain MRI features plus incident dementia diagnoses during follow-...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990419/ https://www.ncbi.nlm.nih.gov/pubmed/33427739 http://dx.doi.org/10.3233/JAD-201080 |