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Hemochromatosis Mutations, Brain Iron Imaging, and Dementia in the UK Biobank Cohort

BACKGROUND: Brain iron deposition occurs in dementia. In European ancestry populations, the HFE p.C282Y variant can cause iron overload and hemochromatosis, mostly in homozygous males. OBJECTIVE: To estimate p.C282Y associations with brain MRI features plus incident dementia diagnoses during follow-...

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Detalles Bibliográficos
Autores principales:	Atkins, Janice L., Pilling, Luke C., Heales, Christine J., Savage, Sharon, Kuo, Chia-Ling, Kuchel, George A., Steffens, David C., Melzer, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990419/ https://www.ncbi.nlm.nih.gov/pubmed/33427739 http://dx.doi.org/10.3233/JAD-201080

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