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DNA Repair in Huntington’s Disease and Spinocerebellar Ataxias: Somatic Instability and Alternative Hypotheses

The use of genome wide association studies (GWAS) in Huntington’s disease (HD) research, driven by unbiased human data analysis, has transformed the focus of new targets that could affect age at onset. While there is a significant depth of information on DNA damage repair, with many drugs and drug t...

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Detalles Bibliográficos
Autores principales: Maiuri, Tamara, Hung, Claudia L.K., Suart, Celeste, Begeja, Nola, Barba-Bazan, Carlos, Peng, Yi, Savic, Natasha, Wong, Timothy, Truant, Ray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990435/
https://www.ncbi.nlm.nih.gov/pubmed/33579859
http://dx.doi.org/10.3233/JHD-200414