Shear-Induced Amyloid Aggregation in the Brain: V. Are Alzheimer’s and Other Amyloid Diseases Initiated in the Lower Brain and Brainstem by Cerebrospinal Fluid Flow Stresses?

Amyloid-β (Aβ) and tau oligomers have been identified as neurotoxic agents responsible for causing Alzheimer’s disease (AD). Clinical trials using Aβ and tau as targets have failed, giving rise to calls for new research approaches to combat AD. This paper provides such an approach. Most basic AD res...

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Detalles Bibliográficos
Autor principal: Trumbore, Conrad N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990457/
https://www.ncbi.nlm.nih.gov/pubmed/33386802
http://dx.doi.org/10.3233/JAD-201025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990457/
https://www.ncbi.nlm.nih.gov/pubmed/33386802
http://dx.doi.org/10.3233/JAD-201025

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