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Archaeal chromatin ‘slinkies’ are inherently dynamic complexes with deflected DNA wrapping pathways

Eukaryotes and many archaea package their DNA with histones. While the four eukaryotic histones wrap ~147 DNA base pairs into nucleosomes, archaeal histones form ‘nucleosome-like’ complexes that continuously wind between 60 and 500 base pairs of DNA (‘archaeasomes’), suggested by crystal contacts an...

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Detalles Bibliográficos
Autores principales: Bowerman, Samuel, Wereszczynski, Jeff, Luger, Karolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990501/
https://www.ncbi.nlm.nih.gov/pubmed/33650488
http://dx.doi.org/10.7554/eLife.65587