Seipin Deficiency Accelerates Heart Failure Due to Calcium Handling Abnormalities and Endoplasmic Reticulum Stress in Mice

Seipin deficiency can induce hypertrophic cardiomyopathy and heart failure, which often leads to death in humans. To explore the effects and the possible mechanisms of Seipin deficiency in myocardial remodeling, Seipin knockout (SKO) mice underwent transverse aortic constriction (TAC) for 12 weeks....

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Detalles Bibliográficos
Autores principales: Wu, Xiaoyue, Liu, Xuejing, Wang, Huan, Zhou, Zihao, Yang, Chengzhi, Li, Zijian, Zhang, Youyi, Shi, XiaoLu, Zhang, Ling, Wang, Yuhui, Xian, Xunde, Liu, George, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990891/
https://www.ncbi.nlm.nih.gov/pubmed/33778025
http://dx.doi.org/10.3389/fcvm.2021.644128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990891/
https://www.ncbi.nlm.nih.gov/pubmed/33778025
http://dx.doi.org/10.3389/fcvm.2021.644128

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