Oleandrin, a cardiac glycoside, induces immunogenic cell death via the PERK/elF2α/ATF4/CHOP pathway in breast cancer

Chemotherapeutic agents have been linked to immunogenic cell death (ICD) induction that is capable of augmenting anti-tumor immune surveillance. The cardiac glycoside oleandrin, which inhibits Na(+)/K(+)-ATPase pump (NKP), has been shown to suppress breast cancer growth via inducing apoptosis. In th...

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Detalles Bibliográficos
Autores principales: Li, Xiaoxi, Zheng, Jian, Chen, Shi, Meng, Fan-dong, Ning, Jing, Sun, Shu-lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990929/
https://www.ncbi.nlm.nih.gov/pubmed/33762577
http://dx.doi.org/10.1038/s41419-021-03605-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990929/
https://www.ncbi.nlm.nih.gov/pubmed/33762577
http://dx.doi.org/10.1038/s41419-021-03605-y

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