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Peptide-based scaffolds for the culture and maintenance of primary human hepatocytes

We report here the use of a nanofibrous hydrogel as a 3D scaffold for the culture and maintenance of functional primary human hepatocytes. The system is based on the cooperative assembly of a fiber-forming peptide component, fluorenylmethyloxycarbonyl-diphenylalanine (Fmoc-FF), and the integrin-bind...

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Detalles Bibliográficos
Autores principales: MacPherson, Douglas, Bram, Yaron, Park, Jiwoon, Schwartz, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990934/
https://www.ncbi.nlm.nih.gov/pubmed/33762604
http://dx.doi.org/10.1038/s41598-021-86016-5