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Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis

INTRODUCTION: Likely due to ignored heterogeneity in disease pathophysiology, osteoarthritis (OA) has become the most common disabling joint disease, without effective disease-modifying treatment causing a large social and economic burden. In this study we set out to explore responses of aged human...

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Detalles Bibliográficos
Autores principales: Houtman, Evelyn, van Hoolwerff, Marcella, Lakenberg, Nico, Suchiman, Eka H. D., van der Linden-van der Zwaag, Enrike, Nelissen, Rob G. H. H., Ramos, Yolande F. M., Meulenbelt, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991015/
https://www.ncbi.nlm.nih.gov/pubmed/33608843
http://dx.doi.org/10.1007/s40744-021-00287-y