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Opposing Effects of TGFβ and BMP in the Pulmonary Vasculature in Congenital Diaphragmatic Hernia

Background: Pulmonary hypertension is the major cause of morbidity and mortality in congenital diaphragmatic hernia (CDH). Mutations in several genes that encode signaling molecules of the transforming growth factor β (TGFβ) and bone morphogenetic protein (BMP) pathways have previously been associat...

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Detalles Bibliográficos
Autores principales: Mous, Daphne S., Buscop-van Kempen, Marjon J., Wijnen, Rene M. H., Tibboel, Dick, Morty, Rory E., Rottier, Robbert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991367/
https://www.ncbi.nlm.nih.gov/pubmed/33777983
http://dx.doi.org/10.3389/fmed.2021.642577